Stable Supply Citrus Aurantium Extract 98% Neohesperidin with CAS 13241-33-3 for Supplement
Introduction of Neohesperidin
Neohesperidin is a natural flavanone glycoside extracted and purified from citrus peels through advanced separation and crystallization technology.
It possesses notable properties including antioxidant, anti-inflammatory, flavor modifying and bitterness masking effects.
Neohesperidin
Purity: 98% (HPLC)
CAS No.: 13241-33-3
Molecular Formula: C28H34O15
Molecular Weight: 610.56
Source: Mainly extracted from bitter orange peel, citrus fruits
Appearance: White to off-white crystalline powder
Solubility: Slightly soluble in cold water, soluble in hot water, methanol and ethanol

Function of Neohesperidin
Neohesperidin, a citrus-derived flavanone glycoside, exerts potent free radical scavenging and anti-inflammatory effects by inhibiting inflammatory factors and modulating stress-related pathways.It protects cardiovascular health by enhancing capillary toughness,improving microcirculation and maintaining normal vascular permeability. Additionally, it regulates intestinal flora, supports liver function by reducing fat accumulation and hepatocyte damage and serves as a key precursor for NHDC—a high-intensity low-calorie sweetener 1,500–2,000 times sweeter than sucrose.
It’s antioxidant and anti-aging properties also make it valuable for skin care, while it aids in balancing blood lipids and alleviating intestinal inflammation.

Application Area of Neohesperidin
1,Food Industry
a,Raw material for synthesizing neohesperidin dihydrochalcone (NHDC) a high-intensity sweetener.
b,Used as a flavor enhancer, bitterness masking agent, and preservative in beverages, candy, baked goods and low-sugar foods.
2,Pharmaceutical & Healthcare Products
a,Cardiovascular health supplements to improve capillary fragility and microcirculation.
b,Antioxidant and anti-inflammatory ingredients for liver protection and metabolic regulation.
c,Used in oral and gastrointestinal healthcare formulations.
3, Cosmetics & Skin Care
a,Antioxidant, anti-aging, and soothing components in creams, serums, and lotions.
b,Inhibits melanin production, brightens skin and relieves redness and sensitivity.
4, Daily Chemical & Oral Care
a,Added in toothpaste, mouthwash and chewing gum to enhance flavor and mask bitterness.
b,Feed & Animal Nutrition
c,Used as a natural antioxidant and growth promoter to improve animal intestinal health and immunity.
Product specification of Neohesperidin
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Neohesperidin,CAS 13241-33-3 Technical Data Sheet |
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Sense Index |
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Appearance |
Light yellow to off-white powder |
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Odor & Taste |
Characteristic |
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Physical-chemical Index |
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Neohesperidin |
98% Min |
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Loss on drying |
5% Max |
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Ash |
5% Max |
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Particle Size |
98% pass 80 mesh |
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Heavy metals |
10ppm Max |
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Lead |
2ppm Max |
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Arsenic |
2ppm Max |
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Mercury |
0.1ppm Max |
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Cadmium |
1ppm Max |
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Hygienic Index |
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Total plate count |
1,000cfu/g Max |
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Mold & yeast |
100cfu/g Max |
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Enterobacteriae |
10cfu/g Max |
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E.Coli |
Absent in 10g |
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Salmonella |
Absent in 25g |
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Statements: Non-Irradiated, Non-GMO |
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Shelf Life: 24 months stored in original packaging away from the light and under the optimal temperature 10~25℃. |
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Packaging: 1kg/aluminium foil bag or 25kg/fiber drum. |
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