Wholesale Natural Sophora Japonica Extract 98% Quercetin Anhydrous/ Dihydrate Pure Quercetin Powder

Quercetin has a wide range of sources and is widely present in the stem bark, flowers, leaves, buds, seeds, and fruits of many plants. The preparation methods currently include extraction and separation, acid hydrolysis, and enzymatic conversion, among which enzymatic conversion is the most practical.

In 2010, the FDA designated quercetin, which is processed and produced from natural products, as a GRAS substance. On July 4, 2025, it was reported that the combination of chemotherapy with dasatinib and quercetin can clear chemotherapy-induced aging fibroblasts.

Antitumor and antiplatelet aggregation
Quercetin can significantly inhibit the action of cancer promoting agents, suppress the growth of malignant cells in vitro, and inhibit the synthesis of DNA, RNA, and protein in Ehrlich ascites cancer cells.

Quercetin has inhibitory effects on platelet aggregation and the release of 5-hydroxytryptamine (5-HT). Quercetin has a significant inhibitory effect on platelet aggregation induced by ADP, thrombin, and platelet activating factor (PAF), with the strongest inhibitory effect on PAF. Quercetin can also significantly inhibit the release of 3H-5-HT from rabbit platelets induced by thrombin [5-7].
The study of food test data shows that quercetin can play an antithrombotic role by inhibiting platelet aggregation and selectively binding to the thrombus on the vascular wall. It can reduce the risk of heart disease and atherosclerosis by reducing the oxidation of LDL cholesterol [7].
antioxidant
The antioxidant capacity of quercetin is 50 times that of vitamin E and 20 times that of vitamin C.

It can eliminate free radicals in three ways:
1) Eliminate it directly by oneself;
2) Through enzymes that clear free radicals;
3) Inhibit the production of free radicals;
This ability to clear reactive oxygen species also helps alleviate inflammatory reactions [8-9].
The in vitro and in vivo evaluation of the biological activity of quercetin involves multiple cell lines and animal models, but the metabolic mechanism of quercetin in the human body is still unclear. Therefore, further large-scale clinical studies are needed to determine the appropriate dosage and form of quercetin for treating this disease.  

Summarizing the current research results, it has antioxidant, anti-inflammatory, anti-virus, anti-tumor, hypoglycemic, lipid-lowering, immune regulation and other biological activities and extensive pharmacological effects, and has very important clinical significance in the treatment of bacterial infection, viral infection, tumor, diabetes, hyperlipidemia and immune system diseases

Quercetin, a naturally occurring flavonoid abundantly found in fruits, vegetables, and grains, has garnered significant scientific interest due to its diverse biological activities. Its applications span several key fields, including pharmaceuticals, nutraceuticals, cosmetics, and functional foods.

In the pharmaceutical and nutraceutical sectors, quercetin is primarily investigated for its potent antioxidant and anti-inflammatory properties. It is explored as a therapeutic agent or supplement for managing chronic diseases such as cardiovascular disorders, by improving endothelial function and reducing oxidative stress. Its anti-cancer potential is a major area of research, where it is studied for its ability to induce apoptosis and inhibit proliferation in various cancer cell lines. Furthermore, quercetin's immunomodulatory effects are leveraged to support immune health, and its potential neuroprotective roles in conditions like Alzheimer's disease are under active investigation.

The cosmetics and skincare industry extensively utilizes quercetin for its protective benefits against environmental stressors. As a powerful antioxidant, it helps neutralize free radicals generated by UV radiation and pollution, thereby preventing premature skin aging, reducing the appearance of wrinkles, and improving skin elasticity. Its anti-inflammatory action also makes it suitable for formulations aimed at soothing irritated or sensitive skin.

In the realm of functional foods and beverages, quercetin is incorporated as a natural bioactive ingredient to enhance the health profile of products. Its stability and bioavailability are key considerations in product development. Additionally, in agriculture, quercetin is studied for its potential use as a natural additive in animal feed to improve growth performance and immune status, reducing the reliance on antibiotics.

In summary, quercetin's multifaceted applications, driven by its fundamental antioxidant mechanism, make it a valuable compound across health, wellness, and cosmetic domains, with ongoing research continuously expanding its potential uses.